- The Buffalo Bills defense is the only team in the NFL that ranks in the top five in the following major defensive categories: sacks (1st - 49), interceptions (T2nd – 19), third down percentage (2nd – 33.33), points per game (T4th – 18.1), total yards per game (5th – 313.4).
- After recording a special teams touchdown on Marcus Thigpen's 75-yard punt return, the Bills collected their fourth win this season (4-0) when producing a defensive or special teams touchdown.
- The Bills completed their home schedule with a 5-3 record and have posted a home record of .500 or above in each of the last four seasons (5-3 in 2011, 4-4 in 2012, 2013).
- Buffalo improved to 6-0 against the Green Bay Packers at home ... The Bills were 4-0 in against their NFC North opponents and swept interconference opponents for the first time since 2004 (4-0 vs. NFC West).
- Buffalo closed Sunday's game with Mario Williams sack and forced fumble to secure its 21-13 lead. The team continues to lead the NFL with 49 sacks and the total is also tied for the third-highest in team history (49 in 1995).
- Marcus Thigpen's 75-yard punt return touchdown was the longest of his punt return of his career ... The play was Buffalo's only touchdown of the game and the team's first punt return touchdown since Leodis McKelvin's 79-yard return vs. Miami on November 15, 2012.
- In his 15th NFL game, safety Bacarri Rambo recorded his first two interceptions of his career on Sunday.
- With 850 receiving yards on the season, wide receiver Sammy Watkins now holds the Bills rookie record for most receiving yards in a season passing Lee Evans' record of 843 yards in 2004.
- With a 51-yard field goal on Sunday, kicker Dan Carpenter set a new season-high with five 50-yard field goals in 2014 ... Carpenter has nine 50-yard field goals the past two seasons and is tied for third in the NFL during that time span. The total also ranks as the third-most by a Bills kicker in team history.
- Linebacker Preston Brown recorded six tackles on Sunday to raise his season total to 101 and became the second consecutive Bills rookie with 100 tackles (159 – Kiko Alonso, 2013). This marks the first time in team history that two Bills rookies has recorded 100 tackles in consecutive seasons.
- Running back Fred Jackson now has 312 career receptions and ranks fifth on the Bills all-time receptions list passing Josh Reed's 311 ... Jackson rushed for a team season-high 71 yards on Sunday.