- The Bills defense shut down the Texans' rushing attack by holding Houston to 37 yards on 24 attempts and a 1.5 yards per carry average. The Bills defense ranks first in the AFC and second in the NFL allowing 2.9 yards per carry. The Bills ranks second in the AFC and third in the NFL allowing 71.5 rushing yards per game.
- The Bills defense accounted for three turnovers on Sunday and is now tied for third in the NFL with a 5 turnover margin.
- EJ Manuel threw a career-long 80-yard touchdown pass to Mike Williams in the fourth quarter. The play is the longest pass in the AFC thus far in the 2014 season.
- Manuel also*tied a career high* with two touchdown passes (Five-yard TD pass to Sammy Watkins; 80-yard TD to Mike Williams).
- Watkins has 17 receptions in the first four games of the season – the total is the third-most by a Bills rookie in that time span. Jerry Butler (21 in 1979) and Joe Cribbs (18 in 1980) rank ahead of Watkins.
- WR Mike Williams established a career-high with his 80-yard touchdown reception. On the play, Williams passed the 3,000-yard receiving mark for his career.
- LB Nigel Bradham registered his first NFL sack in the first quarter and then his first NFL interception in the first play of the third quarter. On the latter play, Bradham injured his knee in a collision and did not return to the game. Bradham was the first Bill to post a sack and interception in the same game since Jairus Byrd on November 17, 2013 vs. NY Jets.
- CB Leodis McKelvin has tied a personal single-season best with two interceptions thus far in 2014. McKelvin posted two interceptions in both 2008 and 2010 ... McKelvin is tied for first in the AFC with two interceptions.
- LB Brandon Spikes forced his first fumble as a Bill and the sixth of his NFL career. The fumble was recovered by Da'Norris Searcy and converted into a touchdown on Buffalo's subsequent drive. Spikes last forced a fumble on November 22, 2012 at the NY Jets (with New England).
- RB Fred Jackson produced a team-high 85 scrimmage yards (52 yards on six receptions and 33 rushing yards on seven carries).
- CJ Spiller returned three kickoffs for an average of 27.3 yards against Houston ... Spiller leads the AFC with a 35.9 kickoff return average ... The Bills rank first in the NFL with a 26.9 average drive starting point.
- DT Marcell Dareus eclipsed the 20-sack mark and now has 20.5 career sacks.
