- In Buffalo's five wins, Sammy Watkins is averaging 102.8 yards per game and 17.13 yards per reception and has a total of four touchdowns.
- Watkins leads or is tied for the lead among NFL rookies in the following five categories: receiving yards (590), yards per game (73.8), longest reception (84 yards), touchdown receptions (five, tied with Kelvin Benjamin-CAR), 20-plus yard receptions (nine, tied with Kelvin Benjamin-CAR), first downs (29).
- With 157 receiving yards, Sammy Watkins became the first Bills rookie wide receiver to post consecutive 100-yard receiving games (122 on 10/19/14 vs. Minnesota).
- Watkins also set a team single-game record with a 52.3 yards per reception average (three receptions for 157 yards) breaking the old mark of 43.60 set by Elbert Dubenion on 10/24/64 vs. NY Jets (five receptions for 218 yards).
- The Bills became the first NFL team to post three interceptions in the first quarter since Arizona had three on 11/18/12 at Atlanta.
- The Bills registered four interceptions (one each by Stephon Gilmore, Preston Brown, Aaron Williams and Da'Norris Searcy) on Sunday and now lead the NFL with 12 in 2014 ... The Bills also rank third in the NFL with a plus-seven turnover margin.
- Sunday marked the second game in Bills history in which the team scored 40-plus points and had less than 300 yards of total offense (last time 9/17/61 vs. NY Titans in 41-31 win) ... Sunday's 43-point total was the highest by a Bills team since its 49-31 victory on 11/21/10 at Cincinnati
- The Bills' 6 turnover differential was tied for the second-most in team history – last time it happened on 12/5/04 at Miami (seven takeaways vs. one turnover).
- After 4.0 sacks on Sunday, the Bills now lead the NFL with 28 sacks this season. The total is the second-most in team history through eight games trailing only 30 in 1997.
- Kyle Williams posted 1.5 sacks on Sunday and now ranks tied for 10th on the team's all-time sack list with Jeff Wright at 31.5 sacks.
- Kyle Orton became the first NFL quarterback to throw four touchdown passes with 10 or less completions since Bubby Brister with Pittsburgh vs. Cleveland on 12/23/90. ... Orton's four touchdown passes tied a career-high.
- Orton ranks sixth in the NFL with an 8.0 average yards per pass attempt.
- Orton leads the NFL in fourth quarter passer rating at 132.5.
- Dan Carpenter played in his 100th NFL game on Sunday and totaled 13 points. Carpenter ranks fourth in the NFL with 66 points on the season.