5. Bills take Houston

While it's well-documented that Bills fans are willing to travel near and far to cheer for their team on the road, this week Buffalo will have additional reinforcements from several Bills Legends. Former Bills such as Thurman Thomas, Darryl Talley, Antowain Smith, Kenneth Davis, Terrence McGee, Spencer Johnson and DaShon Polk, to name a few, will reunite in The Lone Star State for a Bills-themed weekend. Starting with a Legends event on Saturday evening, the crew will then make their way to the Texans' house to support the Bills. 

Additionally, with two large Bills Backers Chapters in the area – Bills Backers of Houston and North Houston Bills Backers – you can expect to see Bills fans a plenty at the matchup.

4. Not their first rodeo

For a few Bills players and coaches, the trip to Houston is one that they're familiar with. In Jerry Hughes' case, the outing is a homecoming of sorts. Hughes, who grew up in Sugar Land, Texas, southwest of Houston, also attended high school just 23 miles away from the Texans' stadium. Bills defensive backs coach John Butler also has ties to Houston, spending the 2014-17 seasons with the Texans as the team's secondary coach.

3. Keep it movin'

Last week, ball carriers LeSean McCoy and Chris Ivory provided the extra steam the Bills needed to come away with a win over the Titans – especially on the team's victory-sealing drive. The duo earned every inch of their combined 128 yards, evading tackles and dragging the pile on a few impressive, hard-fought runs. Setting the ground game in motion, the veterans will look to keep things moving this week when they square off against a tough Texans run defense.

2. Hausch Money could hit the jackpot

Bills veteran kicker Stephen Hauschka has certainly earned his nickname "Hausch Money" over the course of his 11-year career. From establishing a new NFL record last season by converting 13 consecutive kicks through the uprights from 50-plus yards to game-winning field goals, Hauschka has been nothing less than clutch.

This weekend, he's looking to cash in on his 1,000th career point and needs just 13 to make it happen. If he succeeds, Hauschka will become just the 10th active player to hit the mark.

1. Restricted area: No touchdowns allowed

There's no question that Buffalo's defense is connecting. After putting together back-to-back inspired performances, this tough, tight-knit group, has proven one difficult clique to crack. And no, you can't sit with them.

A stingy bunch, the Bills 'D' isn't too keen on letting opposition in, especially to the end zone. In Week 5, the unit limited Tennessee to strictly field goals and are fixing to do the same against the Texans. If the Bills manage the feat, it'll signify the first time they've kept their opponent from scoring a touchdown in consecutive games since 1999. A key component in both of Buffalo's wins this season, the defense will look to help the team make it three this week.