Highlight: Isaiah McKenzie's 24-yard catch and run

Buffalo Bills quarterback Josh Allen's best plays from his four touchdown, 430-yard game vs. the Detroit Lions in Week 15 of the 2024 NFL season.

Watch the Buffalo Bills' top plays vs. the Detroit Lions from Week 15 of the 2024 NFL season.

Watch highlights from the Week 15 matchup between the Buffalo Bills and the Detroit Lions during the 2024 NFL season. Bills won 48-42 in Detroit.

Watch the best Buffalo Bills plays from running backs Ty Johnson, James Cook and Ray Davis vs. Lions during Week 15 season.

Buffalo Bills wide receiver Mack Hollins nearly takes onside kick to the house.

Buffalo Bills quarterback Josh Allen floats it running back Ray Davis to extend lead to 45-28.

Buffalo Bills quarterback Josh Allen delivers perfect to tight end Dalton Kincaid for 29-yard gain.

Khalil Shakir catches for a 3-yard Touchdown vs. Detroit Lions, 12/15/2024

Buffalo Bills safety Christian Benford rips ball to force fumble from Detroit Lions wide receiver Amon-Ra St. Brown, Bills linebacker Matt Milano recovers.

James Cook rushes for a 41-yard touchdown vs. Detroit Lions, 12/15/2024

Josh Allen with a pass completion to Keon Coleman for a 64-yard Gain vs. Detroit Lions, 12/15/2024

James Cook rushes for a 6-yard touchdown vs. Detroit Lions, 12/15/2024. Cook scored his 12th rushing touchdown of the season.

Buffalo Bills quarterback Josh Allen cruises in for his second rushing TD of game uncotuched.

Buffalo Bills quarterback Josh Allen extends play, slings it to running back James Cook for 28-yard gain.

Buffalo Bills quarterback Josh Allen QB sneaks his way in for first score of game. Allen now has 20+ passing touchdowns and 10+ rushing touchdowns in consecutive seasons - 2nd player in NFL history to achieve this feat.

Buffalo Bills quarterback Josh Allens drops 33-yard pass in running back Ty Johnson's basket.

Here's everything you need to know when the Buffalo Bills play the Detroit Lions Week 15 of the 2024 NFL season.

Watch all of Buffalo Bills quarterback Josh Allen best plays from his 6-touchdown game against the Los Angeles Rams in Week 14 of the 2024 NFL regular season. Allen became the first NFL player with three passing touchdowns and three rushing touchdowns in a regular season game.

Buffalo Bills vs. Los Angeles Rams highlights | Week 14. The Bills lost a thriller 44-42 as Josh Allen produced six total touchdowns in the loss.

Watch Buffalo Bills wide receiver Khalil Shakir's Week 14 highlights as he caught five passes for 106 yards against the Los Angeles Rams.

Josh Allen rushes for a 1-yard touchdown vs. Los Angeles Rams, 12/08/2024. Allen became the first NFL player with three passing touchdowns and three rushing touchdowns in a regular season game.

Mack Hollins catches for a 21-yard Touchdown vs. Los Angeles Rams, 12/08/2024

Buffalo Bills quarterback Josh Allen's 30-yard rush vs. Los Angeles Rams involves a lot of open space for BUF's QB1

Josh Allen rushes for a 1-yard touchdown vs. Los Angeles Rams, 12/08/2024. Josh Allen now has five career games with two passing touchdowns and two rushing touchdowns - most in NFL history.

Josh Allen with a pass completion to Khalil Shakir for a 34-yard Gain vs. Los Angeles Rams, 12/08/2024