James Cook bounces it outside for 25-yard run | Bills vs. Pats

Buffalo Bills' running back James Cook kicks off the Bills' first possession of the second half with a 25-yard run.

Watch highlights from the Week 16 matchup between the New England Patriots and the Buffalo Bills during the 2024 NFL season. The Bills won 24-21 at Highmark Stadium.

Watch the best plays from Buffalo Bills' running back James Cook's 2-touchdown game vs. the New England Patriots in Week 16 of the 2024 NFL season.

Watch the best plays by the Buffalo Bills against the New England Patriots in Week 16 of the 2024 NFL season.

Taron Johnson (Buffalo Bills) with a Defensive Touchdown vs. New England Patriots, 12/22/2024

Buffalo Bills' defensive back Cam Lewis makes his first NFL interception with a diving attempt on a pass from New England Patriots' quarterback Drake Maye into the end zone.

Greg Rousseau forced New England Patriots' running back Rhamondre Stevenson to fumble on his way down to the ground, and Buffalo Bills' linebacker Dorian Williams recovers.

The Buffalo Bills take a 17-14 lead vs. the New England Patriots thanks to a 50-yard field goal from kicker Tyler Bass.

Josh Allen with a 4-yard touchdown pass to James Cook vs. New England Patriots, 12/22/2024

Buffalo Bills' quarterback Josh Allen and wide receiver Keon Coleman combine for a 17-yard pass and catch.

James Cook rushes for a 46-yard touchdown vs. New England Patriots, 12/22/2024. Bills tied the franchise record for most rushing touchdowns in a season (29 in 2016).

Buffalo Bills' quarterback Josh Allen's 13-yard pass is scooped off the turf by Bills' tight end Dawson Knox.

Buffalo Bills quarterback Josh Allen's best plays from his four touchdown, 430-yard game vs. the Detroit Lions in Week 15 of the 2024 NFL season.

Watch the Buffalo Bills' top plays vs. the Detroit Lions from Week 15 of the 2024 NFL season.

Watch highlights from the Week 15 matchup between the Buffalo Bills and the Detroit Lions during the 2024 NFL season. Bills won 48-42 in Detroit.

Watch the best Buffalo Bills plays from running backs Ty Johnson, James Cook and Ray Davis vs. Lions during Week 15 season.

Buffalo Bills wide receiver Mack Hollins nearly takes onside kick to the house.

Buffalo Bills quarterback Josh Allen floats it running back Ray Davis to extend lead to 45-28.

Buffalo Bills quarterback Josh Allen delivers perfect to tight end Dalton Kincaid for 29-yard gain.

Khalil Shakir catches for a 3-yard Touchdown vs. Detroit Lions, 12/15/2024

Buffalo Bills safety Christian Benford rips ball to force fumble from Detroit Lions wide receiver Amon-Ra St. Brown, Bills linebacker Matt Milano recovers.

James Cook rushes for a 41-yard touchdown vs. Detroit Lions, 12/15/2024

Josh Allen with a pass completion to Keon Coleman for a 64-yard Gain vs. Detroit Lions, 12/15/2024

James Cook rushes for a 6-yard touchdown vs. Detroit Lions, 12/15/2024. Cook scored his 12th rushing touchdown of the season.

Buffalo Bills quarterback Josh Allen cruises in for his second rushing TD of game uncotuched.