James Cook seals the game with two-yard touchdown run | Bills at Colts

James Cook rushes for a 2-yard touchdown vs. Indianapolis Colts, 11/10/2024

Watch the Buffalo Bills' top plays vs. the Indianapolis Colts from Week 10 of the 2024 NFL season.

Watch highlights from the Week 10 matchup between the Buffalo Bills and the Indianapolis Colts during the 2024 NFL season. Bills won 30-20.

Buffalo Bills safety Taylor Rapp corrals Indianapolis Colts quarterback Joe Flacco's overthrown pass for the Bills' third interception of the day.

Buffalo Bills kicker Tyler Bass' 28-yard field goal boosts Bills' lead to 23-13 over the Indianapolis Colts.

Buffalo Bills defensive Quinton Jefferson devours Indianapolis Colts quarterback Joe Flacco for a 10-yard sack.

Greg Rousseau (Buffalo Bills) with a Spectacular Sack vs. Indianapolis Colts, 11/10/2024

Buffalo Bills defensive back Taron Johnson's blitz gets home for a sack on Indianapolis Colts quarterback Joe Flacco.

Buffalo Bills kicker Tyler Bass' 47-yard field goal boosts the Bills' lead to 20-13 over the Indianapolis Colts at halftime.

Off-platform dime! Buffalo Bills quarterback Josh Allen's improv lob to wide receiver Mack Hollins goes for a 44-yard gain against the Indianapolis Colts.

Josh Allen rushes for a 13-yard touchdown vs. Indianapolis Colts, 11/10/2024. He ties OJ Simpson for 2nd place on the team's all-time rushing touchdown list.

Buffalo Bills quarterback Josh Allen goes deep to tight end Dawson Knox for a 34-yard gain and red-zone access against the Indianapolis Colts.

Buffalo Bills wide receiver Mack Hollins slides for a 16-yard first down reception agains the Indianapolis Colts.

Buffalo Bills quarterback Josh Allen's 17-yard laser to wide receiver Curtis Samuel gets the Bills to midfield vs. the Indianapolis Colts.

Buffalo Bills kicker Tyler Bass' 29-yard field goal gives the Bills the early 10-0 lead over the Indianapolis Colts.

Big-man interception! Buffalo Bills defensive tackle Austin Johnson's second takeaway of 2024 comes vs. the Indianapolis Colts quarterback Joe Flacco in Week 10.

Taron Johnson intercepts the Joe Flacco pass vs. Indianapolis Colts, 11/10/2024. His third career pick six.

Here's everything you need to know when the Buffalo Bills play the Indianapolis Colts week 10 of the 2024 NFL season.

Watch the Buffalo Bills' best play from every week at midseason of the 2024 NFL season!

Watch the Buffalo Bills' top plays vs. the Miami Dolphins from Week 9 of the 2024 NFL season. Buffalo won 30-27.

Watch the best plays by Buffalo Bills quarterback Josh Allen from his 3-TD game during Week 9 of the 2024 season.

Watch highlights from Buffalo's 30-27 victory over Miami.

Buffalo Bills kicker Tyler bass drills a 61-yard field goal to give the Bills a late 30-27 lead vs. the Miami Dolphins.

Quintin Morris catches for a 2-yard Touchdown vs. Miami Dolphins as Bills take a 27-20 lead, 11/03/2024

A play-action pass from Buffalo Bills quarterback Josh Allen to wide receiver Keon Coleman ends with a 21-yard gain for the Bills vs. the Miami Dolphins.