The Buffalo Bills will be without DE Greg Rousseau (ankle) and LB Tremaine Edmunds (groin/heel) for Thursday's Thanksgiving game against the Detroit Lions. Head coach Sean McDermott ruled out both players during his weekly appearance on WGR550.
This will Rousseau's third consecutive game missed and Edmunds' second in a row.
As for DE A.J. Epenesa, he is listed as doubtful and center Mitch Morse is listed as questionable.
The Bills' full injury report will be updated later on Wednesday as the team prepares to head to Detroit.