Their designations are not surprising given their practice participation this week. DE Shaq Lawson, WR Andre Roberts and CB Levi Wallace are all listed as questionable for Saturday's Wild Card game against Houston.
Lawson and Roberts were on the practice field for the third straight day on Thursday, so they appear to be trending in the right direction despite being limited all week. Both players missed Buffalo's regular season finale last Sunday with hamstring and foot injuries suffered in Week 16.
Nsekhe and Wallace were both injured in last week's game against the Jets but were able to return to practice in a limited capacity as well.
If Wallace can't play Saturday he'll be replaced in the lineup by Kevin Johnson, who has platooned with him at right cornerback through the second half of the regular season.
The situation is much the same with Nsekhe. If he can't play, Cody Ford will go start to finish at right tackle. The two offensive linemen were also rotating at the right tackle spot when both were healthy.
As the Bills prepare to play the Houston Texans in the Wild Card round, scroll through to view photos from previous appearances by the Bills in the postseason.
Buffalo Bills cornerback Nate Odomes (37) looks for running room after intercepting a pass from Los Angeles Raiders quarterback Jay Schroeder in the second quarter of AFC Championship game in Buffalo Sunday, Jan. 21, 1991. The Bills beat Los Angeles 51-3 to advance to the Super Bowl. (AP Photo/Mark Duncan)
Buffalo Bills defensive end Bruce Smith enters the field for Super Bowl XXV January 27, 1991 in Tampa before 73,813 fans at Tampa Stadium. (AP Photo / Al Messerschmidt)
Buffalo Bills' Carlton Bailey runs in for a touching after a pass interception during the third quarter of their AFC Championship game against the Denver Broncos, Sunday Jan.12, 1992 at Rich Stadium in Orchard Park, N.Y. The Bills went on the beat the Broncos 10-7. (AP Photo/Mark Duncan)
Buffalo Bills wide receiver Andre Reed (83) catches one of his four passes during the AFC Divisional Playoff, a 37-14 victory over the Kansas City Chiefs on January 5, 1992, at Rich Stadium in Orchard Park, New York. (AP Photo / Al Messerschmidt)
Buffalo Bills quarterback Jim Kelly sets for a snap at midfield while Washington Redskins linebacker Wilbur Marshall rushes upfield during Super Bowl XXVI on January 26, 1992, at the Hubert H. Humphrey Metrodome in Minneapolis, Minnesota. (AP Photo / Al Messerschmidt)
January 3, 1993 | Oilers vs. Bills
January 3, 1993 | Oilers vs. Bills
Buffalo Bills injured starting quarterback Jim Kelly, left, congratulates his backup Frank Reich after a fourth quarter touchdown pass against the Pittsburgh Steelers in Pittsburgh on Saturday, Jan. 10, 1993. The Reich led Bills beat the Steelers 24-3 to advance to the AFC Championship game against Miami. (AP Photo/Bill Sikes)
Buffalo Bills receiver Don Beebe jumps with joy after the Bills beat the Pittsburgh Steelers 24-3 in the AFC playoff game in Pittsburgh on Saturday, Jan. 9, 1993. (AP Photo/Bill Sikes)
Buffalo Bills running back Thurman Thomas runs against the Miami Dolphins during the AFC Championship game in Miami on Jan. 21, 1993. (AP Photo/Rusty Kennedy)
Dallas Cowboys running back Emmitt Smith (22) picks up yardage under Buffalo Bills linebacker Cornelius Bennett during the first quarter of Super Bowl XXVII in Pasadena, Jan. 31, 1993. (AP Photo/Rick Bowmer)
Buffalo Bills' running back Kenneth Davis (23) dives over the top for a Second quarter touch down against the Los Angeles Raiders during, NFL playoff game, Saturday, Jan. 15, 1994 in Orchard Park, N.Y. (AP Photo/Bill Sikes)
Buffalo Bills back Thurman Thomas (34) jumps in the air as he celebrates his second quarter touchdown against Los Angeles Raiders, Sunday, Jan 15 ,1994 in Orchard Park, NY . The Bills beat defeated the Raiders 29-23. (AP Photo/Bill Sikes)
Buffalo Bills wide receiver Andre Reed (83) hauls in a 28-yard pass under pressure from Kansas City Chiefs corner back Bruce Pickens (39) in the first quarter during the AFC Championship game on Sunday, Jan. 23, 1994 at Rich Stadium in Orchard Park, N.Y. The pass set up Buffalo?s first touchdown. (AP Photo/Mark Duncan)
Buffalo Bills, from Left, Bill Brooks, Andre Reed, Mickey Washington, Bruce Smith (looking away), Pete Metzelaars (standing), Carwell Gardner, and Nate Odomes (reaching) celebrate in their Locker room with the Lamar Hunt Trophy, signifying their win of the AFC title after beating the Kansas City Chiefs 30-13, Sunday, Jan. 23, 1994, at Rich Stadium in Orchard Park, N.Y. (AP Photo/Bill Sikes)
Marv Levy, head coach for the Buffalo Bills, follows third quarter action against the Dallas Cowboys in Super Bowl XXVIII at the Georgia Dome in Atlanta, Ga., Sunday, Jan. 30, 1994. (AP Photo/Bill Sikes)
Buffalo Bills quarterback Jim Kelly (12) takes the snap out of shotgun formation behind guard Ruben Brown (79) during the Bills 37 - 22 victory over the Miami Dolphins in the 1995 AFC Wild Card playoff game on Dec. 30, 1995 at Rich Stadium in Orchard Park, NY. (Al Messerschmidt via AP)
January 7, 2018 | Bills at Jaguars
January 7, 2018 | Bills at Jaguars
January 7, 2018 | Bills at Jaguars
January 7, 2018 | Bills at Jaguars
January 7, 2018 | Bills at Jaguars
QUESTIONABLE
DE Shaq Lawson – hamstring
OT Ty Nsekhe – ankle
WR Andre Roberts – foot
CB Levi Wallace – ankle
