WR Treylon Burks, Arkansas

The Bills could opt for a CB here, but Burks would be too tempting as a big addition to their offensive firepower. (NFL.com, Daniel Jeremiah)

LB Devin Lloyd, Utah

We've typically had the Bills targeting the secondary in recent mocks but it may be hard to pass on a player of Lloyd's talents here. Every linebacker not named Matt Milano has just one year left on their contracts -- including Tremaine Edmunds and A.J. Klein, and while Buffalo will no doubt re-up some of them, Lloyd has a chance to be special. (CBS Sports, Ryan Wilson)

CB Andrew Booth Jr., Clemson

Swap in Booth for impending free agent Levi Wallace, and the Bills secondary will be even better in 2022. (CBS Sports, Kyle Stackpole)

DT Devonte Wyatt, Georgia

The Buffalo Bills have made it clear that they prioritize investing in the defensive line and as things currently stand, Buffalo has two defensive tackles under contract for the 2022 season. Considering how much Sean McDermott likes to rotate his players up front, more talent is needed. Devonte Wyatt is an explosive penetrator that would wreak havoc next to Ed Oliver and provide the versatility needed to play over the center and as a three-technique. (The Draft Network, Joe Marino)

DE Arnold Ebiketie, Penn State

He had eight sacks among 52 QB pressures in 2021. Buffalo's aging D-line is poised to be stripped of its depth in free agency, but Ebiketie and 2021 rookies Greg Rousseau and Boogie Basham could form a next-gen nucleus up front. (USA Today, Nate Davis)

WR Jahan Dotson, Penn State

With 32-year old Cole Beasley getting a bit old for the position and 34-year old Emmanuel Sanders slated for free agency (and also getting old), the Bills opt here to upgrade their already strong pass catcher corps. Dotson can play all over the formation, runs sharp routes, and perfectly complements the team's Stefon Diggs-Gabriel Davis duo. Getting more playmakers for Josh Allen can't be a bad thing. (The Ringer, Danny Kelly)

S Daxton Hill, Michigan

Hill is part of a Wolverines defense that could end up seeing three players go in Round 1 next spring. He's underrated nationally, but watch him play and it becomes clear pretty quickly that he's in the running for one of the best defensive backs in this class. He's listed as a safety but he can line up anywhere. (CBS Sports, Ryan Wilson)

WR Jameson Williams, Alabama

Jameson Williams has no business being available at No. 25, but after tearing his ACL in the National Championship Game he could go later than his talent level suggests. Should that be the case, his floor should be the Bills' pick.

I believe the Bills' biggest needs remain at the defensive line, but what Williams brings at receiver is exactly what Buffalo needs to keep its fastball and provide Josh Allen another dynamic weapon in the passing game. Williams is a sure-handed receiver with the ability to play outside and from the slot and features a dynamic vertical receiving skill set. He creates separation down the field and he pairs that with exceptional ball skills. (The Draft Network, Joe Marino)

OT Trevor Penning, UNI

Having had success in selecting fellow Northern Iowa lineman Spencer Brown, the Buffalo Bills tack on another one in Trevor Penning. Though he plays a violent game, the Bills can harness Penning's vicious nature with some coaching, and he would immediately improve their line. Penning gets after it in the run game, pancaking anyone in sight, while he also provides a relatively immovable base in pass protection. (Pro Football Network, Cam Mellor)

DT Jordan Davis, Georgia

Davis could very well go higher in the actual draft come April, but the 6-foot-6, 340-pounder's lack of pass-rushing prowess ultimately drops him to the back end of the first round in this mock. He managed only 30 career pressures in college and totaled just 14 in the 2021 season. Of course, his ability to two-gap and positively affect the run game every time he takes the field should ultimately draw interest in the first round. (PFF, Austin Gayle)

CB Trent McDuffie, Washington

Levi Wallace led Buffalo's corners in snaps played and will be an unrestricted free agent next month. Meanwhile, the team's top cornerback (Tre'Davious White) is recovering from a torn ACL. While you can never have too many talented cornerbacks, McDuffie could be off the board much earlier than this and would be a wise choice for the Bills. (SI.com, Kevin Hanson)

CB Kaiir Elam, Florida

The Bills lost Tre White to injury last season, and everything on defense looked a little bleaker afterward. Granted, this is still an excellent unit even without a stud opposite White. But Elam's size and physicality in Buffalo's scheme just makes sense. He'd give Buffalo more upside at the CB2 spot than they've had under Sean McDermott. (The Pewter Report, Jon Ledyard)

OG Kenyon Green, Texas A&M

Back-to-back Aggies see the Bills getting some interior line help. Green played every position on the offensive line this past season out of necessity, but his true position in the NFL is inside. A powerful blocker, Green can develop into a top-tier guard and help tremendously in the run game — assuming the Bills can find a way to stop relying so much on Josh Allen's legs. (SB Nation, James Dator)

EDGE Travon Walker, Georgia

The Bills need improvements along their offensive and defensive lines, and after drafting Greg Rousseau in Round 1 in 2021, they could go back to the D-line this year. Walker is a 6-foot-5, 270-pound project edge rusher who oozes talent. He has physical traits and length that NFL scouts look for, though he's still learning how to put everything together. He played mostly as a tight 5-technique for the Bulldogs, which means he didn't have many opportunities to rush the passer, but he has a high ceiling. He had six sacks last season. (ESPN, Jordan Reid)

CB Kyler Gordon, Washington

The Buffalo Bills were a coin flip in their favor away from hosting the AFC Championship Game but their defense could not secure a stop. Tre White's on-field presence was missed.

Kyler Gordon is a dynamic athlete with nice measurables. He can play inside and out with a versatile matchup profile. The Bills need a true CB2 and Gordon fits the bill (pun intended)! (The Draft Network, Damian Parson)

IOL Zion Johnson, Boston College

Johnson is one of my absolute favorite prospects in the entire 2022 NFL Draft. He looks like he was created in a lab to combat Aaron Donald. He's a monster. On the field, Johnson is an athletic freak who has the strength, flexibility, footwork, and range to be one of the best guards (or centers) in the league within his first few seasons. (The Draft Network, Bryan Perez)

CB Roger McCreary, Auburn

The Bills are a good football team without many glaring weaknesses. That said, Buffalo has an opportunity at No. 25 to consider a few players who might have the goods to walk into a great situation and still add value.

McCreary doesn't necessarily represent an immediate need for Buffalo, but he's an experienced player who held up well in the SEC. He's another player who had a nice Senior Bowl and could be on the rise. (The Athletic, Nick Baumgardner)